A growing start-up has an exciting opportunity for a Biochemical Engineer to join its team. As biochemical engineer, you will be developing the manufacturing process to produce tissue at large-scale. You will ideally be educated to PhD in Chemical Engineering, or a related subject, and have experience in upstream bioprocessing and in in designing, developing and operating bioreactors.
As a Biochemical Engineer in the Bioprocessing team you will be tasked with developing the manufacturing process to produce tissue at large-scale. Your duties will include:
Design, build and operate bioreactor technology at the bench-scale to enable efficient expansion and differentiation of stem cell cultures.
Develop and implement enabling technologies that facilitate bioprocess automation, monitoring and control.
Design, plan, and execute R&D experiments that optimise unit operations and develop the over-arching bioprocess (from raw materials to final product), ensuring that deliverables are successfully met within timeline.
Analyse, summarise, record, and communicate experimental results. Document research findings clearly in an electronic lab book.
Along with team members, provide routine laboratory maintenance, including participating in equipment upkeep, cleaning rotas and laboratory consumables stock management.
Ensure that laboratory and workshop health, safety and quality procedures are followed.
Select, follow, and adapt experimental protocols and generate laboratory SOPs.
Support the preparation of laboratory risk assessments and maintenance of health and safety protocols.
Participate regularly in group meetings and prepare and deliver presentations to project team and internal stakeholders.
Master or PhD in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field.
Experience in one or more of the following areas:
Two or more years' experience in upstream bioprocess development in an industrial or academic setting.
Experience in designing, developing and operating bioreactors.
Substantial experience in aseptic cell culture, ideally with stem cells.
Experience with adherent cell cultures is highly desirable
Experience with statistical software and DoE (design of experiments).
Appreciation of Quality by Design principles.
Ability to develop mechanical designs, PFD, P&IDs, HAZOP and SOPs.
Experience with CAD (e.g. Autodesk) and CFD (e.g. Ansys Fluent) software packages.
Ability to use a programming language (e.g. MATLAB, R) would be a bonus
Computational Fluid Dynamics
Quality By Design (Qb D)