CK Groups US Division are working with growing clinical - stage biotech company who are focused on improving the lives of patients facing life threatening disease with the next generation of antibody therapies.
Our client based in Woburn, Massachusetts and are looking to recruit a Scientist with an immuno-oncology background a permanent basis.
Immuno-oncology Scientist Role:
Responsibilities include to:
Cooperate with internal and external teams to move lead drug candidates from discovery to Investigational New Drug application filings.
Design and execute in vitro T cell phenotypic and functional studies (surface phenotype, proliferation, cellular cytotoxicity, cytokine production, etc.) using human and non-human-derived primary cells and cell lines.
Design and execute pseudoviral neutralization assays.
Perform data analyses using common data analysis and statistical applications (e.g. Excel, Prism, FlowJo).
Record experimental goals, protocols, data, and analyses in an electronic lab notebook in a timely manner.
PhD in Immunology, Cancer Biology, Cell Biology, or similar field.
0-5 years post-PhD experience (academia or industry).
Proficiency in in vitro assays to analyze T cell function, such as flow cytometry, ELISA, and flow cytometry as well as the desire to expand technical proficiencies.
Adept at aseptic cell culture technique.
Effective written and verbal communication skills.
Ability and desire to work within a team and with diverse other teams, both internally and externally.
Ability to present effectively to teams outside of one’s area of expertise.
Ability and desire to work with small animal oncology model.
Experience working in the biotechnology or pharmaceutical industries, preferably in the discovery or development of immuno-oncology or anti-viral therapeutics.
Experience with small animal models relevant to immuno-oncology therapeutic development, including syngeneic tumor models and human tumor xenografts using immune-deficient mouse models with a reconstituted human immune system.
Experience with ex vivo phenotypic and functional analyses of peripheral and tumor-infiltrating immune cell populations.
Experience with pseudoviral neutralization assays.
Experience working with and managing outsourced studies at CRO's.
For more information or to apply for this Immuno-oncology Scientist position, please contact Rob, Amy or Jonathan on (phone number removed) or email (url removed), quoting job ref 50344.
It is essential that applicants hold entitlement to work in the USA
Enzyme Linked Immunosorbent Assay (Elisa)